To compare the efficacy of pain control with use of opioids vs not use of opioids in post-operative period in patients undergoing open thoracotomy surgeries
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/10/037457
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA status I-III
2. Undergoing elective thoracotomy for lung cancer under anaesthesia
Exclusion Criteria
1. Infection at the site of injection for epidural anaesthesia
2. Coagulopathy
3. Spine deformity
4. Pre-existing neurological deficit
5. Patients with a history of chronic pain
6. Patients on opioids preoperatively
7. Drug addicts
8. History of allergy to opioids or local anaesthetic
9. Patients with psychiatric disease
10. Uncontrolled systemic illness (liver disease, cardiac disease, renal failure)
11. Contraindications of epidural anaesthesia
12. Inability to use IV patient controlled analgesia (PCA)
13. Patients requiring postoperative mechanical ventilation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-operative 24 hrs IV fentanyl consumptionTimepoint: 24 hrs
- Secondary Outcome Measures
Name Time Method Oxygenation index (PaO2/FiO2) during two lung ventilation and OLVTimepoint: during two lung ventilation (before initiation of OLV and after end of OLV) and OLV (at 30 min and 60min after initiation of OLV);Pain assessment using NRS during cough/deep breathing at postoperative timeTimepoint: 1 hr, 2 hrs, 4 hrs, 8 hrs, 12 hrs, and 24 hrs post-operative period.;Pain assessment using Numerical rating scale (NRS) at restTimepoint: 1 hr, 2 hrs, 4hrs, 8hrs, 12 hrs, and 24hrs postoperative period.;Patients satisfaction scoreTimepoint: on postoperative day 1;Post-operative complications like nausea vomiting, pruritis etcTimepoint: 24hrs post operative period;Postoperative sedationTimepoint: 1 hr, 2 hrs, 4 hrs, 8 hrs, 12 hrs, and 24 hrs postoperative period. <br/ ><br> <br/ ><br>