MedPath

Modulation of the cardiovascular and immunologic characteristics by aerobic exercise in women with recurrent miscarriage

Recruiting
Conditions
recurrent miscarriage
spontaneous abortions
10000211
10057166
Registration Number
NL-OMON33581
Lead Sponsor
niversitair Medisch Centrum Sint Radboud
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

patients: women with at least two clinically objectified spontaneous abortions

Exclusion Criteria

- auto immune disease
- diabetes
- smoking
- pregnancy
- use of medication known to interfere with cardiovascular system (anti coagulant drugs, antihypertensive drugs, statins, etc...)
- incapability to perform physical exercise

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary outcome of the study: plasmavolume expansion </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Secondary study parameters:<br /><br>Increase exercisetollerance (VO2 max)<br /><br>Increase venous and arterial compliance<br /><br>decrease vascular resistance in uterine artery<br /><br>Increase endothelial functioning<br /><br>Improvement immunologic profile (decrease T-cell activation, decrease NK<br /><br>cytotoxic activity)<br /><br>Increase glucose and lipid profile<br /><br>Improvement cardiac output</p><br>
© Copyright 2025. All Rights Reserved by MedPath