Modulation of ischaemic induced cardiac dysfunction by remote pre-conditioning
Not Applicable
Completed
- Conditions
- Cardiovascular: Single vessel coronary diseaseCirculatory SystemChronic ischaemic heart disease
- Registration Number
- ISRCTN42864201
- Lead Sponsor
- Department of Health (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Added July 2008:
1. Able to consent
2. Age >18
3. Coronary artery disease
4. Normal left ventricular function
Exclusion Criteria
Added July 2008:
1. Diabetes mellitus
2. Valvular heart disease
3. Permanent pacemaker
4. Left bundle branch block (LBBB) on electrocardiogram (ECG)
5. Myocardial infarction in the preceding 3 months
6. Not in sinus rhythm or taking nicorandil or glibenclamide medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Added July 2008:<br>Change in ejection fraction after remote preconditioning, compared to baseline.<br>
- Secondary Outcome Measures
Name Time Method Added July 2008:<br>1. Segmental LV wall tissue velocities<br>2. Rate pressure product<br>3. ECG ST deviation and chest pain score after remote preconditioning, compared to baseline