Influence of Myocardial Shortening on Coronary Tortuosity

Completed

• Conditions: Coronary Artery Vessels; Coronary Artery Disease
• Interventions: Other: No intervention. Observational study

• Registration Number: NCT02741661
• Lead Sponsor: Oregon Health and Science University

Brief Summary

This study is a retrospective analysis where coronary arteriograms are being analyzed to determine whether the presence of tortuous coronary arteries correlate with any specific measures of left ventricular mass or left ventricular function on echocardiography.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2015-07
• Study First Submitted: 2016-04-13
• Study First Submitted QC: 2016-04-15
• Study First Posted: 2016-04-18
• Status Verified: 2016-09
• Primary Completion: 2016-09
• Study Completion: 2016-09
• Last Update Submitted: 2016-09-26
• Last Update Posted: 2016-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• subjects referred for angiography
• echocardiography performed within 3 months.

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Exclusion Criteria

• connective tissue disease
• severe LV dysfunction
• prior coronary artery bypass surgery
• major adverse coronary event between angiogram and echo procedures
• moderate or greater valve disease
• acute coronary syndrome

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Normal coronary arteries	No intervention. Observational study	Patients in whom coronary arteriography has demonstrated no significant tortuosity.
Tortuous coronary arteries	No intervention. Observational study	Patients in whom coronary arteriography has demonstrated tortuous coronary arteries defined as \>1 major bend of \>45 degrees in a major coronary artery

Primary Outcome Measures

Name	Time	Method
Degree of longitudinal shortening	3 months	Measurement of longitudinal shortening of the left ventricle measured on an echocardiography (retrospectively) that was performed within 3 months of the angiogram

Secondary Outcome Measures

Name	Time	Method
LV mass	3 months	Measurement of longitudinal shortening of the left ventricle measured on an echocardiography (retrospectively) that was performed within 3 months of the angiogram

Trial Locations

Locations (1)

OHSU; 🇺🇸 Portland, Oregon, United States