The Role of Newer and Traditional Risk Factors in the Development, Extent and Manifestation of Coronary Artery Disease
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Patients Undergoing Coronary Angiography
- Sponsor
- University of Ioannina
- Enrollment
- 1104
- Locations
- 1
- Primary Endpoint
- The incidence and extent of coronary artery disease between diabetics and non-diabetic patients.
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
In the present study the investigators will measure the extent of coronary artery disease via coronary angiography and the correlating risk factors.
Detailed Description
In the present study the investigators will examine the risk factors determining the development, extent and the manifestation of coronary artery disease. The study will recruit patients undergoing coronary angiography for clinical purposes.
Investigators
MICHALIS LAMPROS
Professor of Cardiology, Medical School, University of Ioannina
University of Ioannina
Eligibility Criteria
Inclusion Criteria
- •Any subject eligible for coronary angiography with or without known CV disease for clinical reasons.
Exclusion Criteria
- •Patients revascularized in the past, with either coronary artery bypass grafting or percutaneous coronary intervention, will be excluded from the study since it is not possible to describe the extent of CAD in these patients.
- •Moderate or severe aortic stenosis.
Outcomes
Primary Outcomes
The incidence and extent of coronary artery disease between diabetics and non-diabetic patients.
Time Frame: Up to four years on average.
We will investigate the incidence, extent and clinical manifestation of coronary artery disease in diabetics and non-diabetics undergoing coronary angiography for clinical reasons.
Secondary Outcomes
- TCF7L2 gene polymorphims and the incidence and extent of coronary artery disease.(Within a maximum period of 4 years.)
- The incidence and extent of coronary artery disease via coronary angiography scores and related biochemical and demographical risk factors.(Up to 4 years on average.)
- The incidence, extent and clinical manifestation of coronary artery disease and the circulating levels of hs-CRP, adipokines and RAGEs.(Up to 4 years on average.)