The Role of Newer and Traditional Risk Factors in the Development, Extent and Manifestation of Coronary Artery Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,104
- 试验地点
- 1
- 主要终点
- The incidence and extent of coronary artery disease between diabetics and non-diabetic patients.
研究概览
简要总结
In the present study the investigators will measure the extent of coronary artery disease via coronary angiography and the correlating risk factors.
详细描述
In the present study the investigators will examine the risk factors determining the development, extent and the manifestation of coronary artery disease. The study will recruit patients undergoing coronary angiography for clinical purposes.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Any subject eligible for coronary angiography with or without known CV disease for clinical reasons.
排除标准
- •Patients revascularized in the past, with either coronary artery bypass grafting or percutaneous coronary intervention, will be excluded from the study since it is not possible to describe the extent of CAD in these patients.
- •Moderate or severe aortic stenosis.
结局指标
主要结局
The incidence and extent of coronary artery disease between diabetics and non-diabetic patients.
时间窗: Up to four years on average.
We will investigate the incidence, extent and clinical manifestation of coronary artery disease in diabetics and non-diabetics undergoing coronary angiography for clinical reasons.
次要结局
- TCF7L2 gene polymorphims and the incidence and extent of coronary artery disease.(Within a maximum period of 4 years.)
- The incidence and extent of coronary artery disease via coronary angiography scores and related biochemical and demographical risk factors.(Up to 4 years on average.)
- The incidence, extent and clinical manifestation of coronary artery disease and the circulating levels of hs-CRP, adipokines and RAGEs.(Up to 4 years on average.)
研究者
MICHALIS LAMPROS
Professor of Cardiology, Medical School, University of Ioannina
University of Ioannina