Impact of impaired digestive /Ama on feces and role of Chitrakadi Vati as of its correction

Phase 3

Not yet recruiting

• Conditions: Functional dyspepsia. Ayurveda Condition: AMADOSHAH,

• Registration Number: CTRI/2023/05/052298
• Lead Sponsor: Institute of Teaching and Research in Ayurveda Jamnagar

Brief Summary

It is a Survey and clinical study to establish Association between symptoms of Ama and Purish characteristic features (if any) and evaluation of Chitrakadi tablet as Amapachana.

As per Ayurveda concept disease are having symptoms of Ama in initial stage, impact of Ama reflects on feces quality of the patients too. To observe these characteristics. Patient having at least three symptoms of Ama i.e., Udara Gaurava (heaviness in abdomen), Mala Sanga (retention of feces/constipation)), Apakti (indigestion) and age between 18 to 50 years.In this study total 100 patients will be registered.  After taking their inform consent recruited subjects will be analysed for presence of Ama and other examinations on the basis of prepared Performa. One day 0 the subject will be undergone for blood test Hb, CBC, ESR, FBS, Lipid profile, Renal function test and Urine routine and microscopic examination, stool microscopic examination. Further feces examination for its characteristics feature in context of Ama will also be assessed.

Out of surveyed patients who are willing to participate and abide to study protocol will be recruited for clinical trial. These patients will be given Chitrakadi tablet 2 tab. Twice a day after meal with luke warm water for 15 days. Patient will be assessed weekly for their impact in symptoms of Ama at the end of 15days, the patients will undergo for stool examination again (physical, microscopic & Jala Nimanjjan and other characteristics features of stool).Subjects will be assessed on the basis of especially prepared proforma incorporating demographic data, symptoms of Ama and details about Mala Parikshana. A closed ended questionnaire will be used to analyse Purishvaha Srotas dushti Lakshana and Sama Mala Lakshana. Written informed consent from subjects will be taken prior to registering them for the study

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2023-03-05
• Study Start: 2023-10-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age between 18 to 50 years Patient having at least three symptoms of Ama i.e., Udara Gaurava (heaviness in abdomen), Mala Sanga (retention of feces/constipation)), Apakti (indigestion).
• Willing to participate and abide to study protocol.

Exclusion Criteria

• Patient below 18 years and above 50 years of age.
• Not willing to participate.
• Patient who is already on ayurveda medication especially for Pachana Chronic debilitating disease like CA, DM, T.B, CKD.
• Ulcerative colitis, peptic ulcer and haemorrhoids, cirrhosis of liver, portal hypertension.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Subsidence generalized defecation related symptoms of Ama	day 0 and 16th day

Secondary Outcome Measures

Name	Time	Method
Absence of stickiness from feces	The stool remains float over water (Jala Santarana)

Trial Locations

Locations (1)

PG Hospital Institute of Teaching and Research in Ayurveda; 🇮🇳 Jamnagar, GUJARAT, India

PG Hospital Institute of Teaching and Research in Ayurveda

🇮🇳Jamnagar, GUJARAT, India

Suresh Panchal

Principal investigator

9662963329

suryapanchal1@gmail.com