Does dietary fructose restriction improve cardio-metabolic health in obesity?

Not Applicable

Recruiting

• Conditions: Cardio-metabolic Health; Obesity; Diet and Nutrition - Obesity; Metabolic and Endocrine - Diabetes; Inflammatory and Immune System - Normal development and function of the immune system

• Registration Number: ACTRN12612000172808
• Lead Sponsor: The University of Newcastle

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-02-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

Aged between 18 – 65 years at initial assessment. Males or female with BMI>30 [BMI = weight (kg)/ height (m)2]

Exclusion Criteria

Are currently on cholesterol lowering drugs e.g. Statins
Are diabetic
Pregnancy or lactation
Are currently on anti-inflammatory drugs e.g. NSAIDs
Are currently on fructose/sugar restricted diets
Diagnosed with any gastrointestinal disorders
Are currently on a weight loss program
Undergone any surgical procedures for obesity
Vegan diet

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine the effect of dietary fructose restriction on:<br>Blood Lipids<br>This outcome will be analysed by blood serum assays.[At baseline, at 6 weeks, at 10 weeks, at 16 weeks];To determine the effect of dietary fructose restriction on:<br>Satiety Hormones<br>This outcome will be analysed by blood serum assays.[At baseline, at 6 weeks, at 10 weeks, at 16 weeks.];To determine the effect of dietary fructose restriction on:<br>Inflammatory Biomarkers & Insulin Resistance<br>This outcome will be analysed by blood serum assays.[At baseline, at 6 weeks, at 10 weeks, at 16 weeks]

Secondary Outcome Measures

Name	Time	Method
IL[NIL]