Efficacy of Platelet-rich plasma vs Steroid Infiltration in management of Low Back Pain: A prospective randomized control study

One of the most prevalent conditions and a major contributor to morbidity and socioeconomic loss in society is low back pain (LBP). It is the second most common cause of disability among adults and a major factor in the physical inactivity of those under 45 years of age. Therefore, it is one of the among the costliest musculoskeletal conditions and has a significant illness burden on society.Non-specific low back pain can be characterized as acute if lasting less than six weeks, sub-acute if lasting between six weeks and three months, and chronic if lasting for longer than three months. Pain is often initiated by instability at a single motion segment, or the result of abnormal motion of vertebral bodies. When assessing patients with LBP, it is important to look for radicular symptoms such as radiating leg pain, sensory deficits, and neurologic lower limb deficits such as reduced reflexes and motor weakness. There are several elements involved in this diseased process. These include facet arthropathy, ligamentum flavum hypertrophy, ossification of the posterior longitudinal ligament, congenitally small neural foramen, ligament laxity, and subluxation, as well as disc degeneration resulting in herniation. Growing older is a factor in these degenerative processes, therefore it seems sense to believe that as life expectancies rise internationally, so too will the prevalence of low back pain.Without the need for invasive or surgical treatments, patients with LBP may typically be treated conservatively with a mix of pharmacological and nonpharmacological therapy. Bed rest, analgesics such acetaminophen and nonsteroidal anti-inflammatory medicines (NSAIDs), muscle relaxants, oral or parenteral steroids, opioids, and therapeutic exercises are all included in conservative therapy. Injections of lumbar or caudal epidural glucocorticoids can be used to alleviate pain if these don’t work. When pain is not relieved by conservative measures or when neurological impairments appear, surgery becomes necessary. Therefore, this study will be conducted to examine the effectiveness of  PRP infiltration versus steroid infiltration (Methyl prednisolone acetate 80 mg/ 2ML) in treatment of facet joint pains.