Effects of Humidified Ventilation on Arterial Oxygenation and Respiratory Mechanics During One Lung Ventilation

Not Applicable

Completed

• Conditions: Lung Cancer
• Interventions: Procedure: Vaporizing humidifier

• Registration Number: NCT01636973
• Lead Sponsor: Yonsei University

Brief Summary

A continuous loss of moisture and heat occurs during mechanical ventilation and prediposes patients to airway damage. Vaporizing humidifier has known to be advantages of improvement of oxygenation and protection of airway damage. However, there is a lack of study about the effect of humidified ventilation on oxygenation and respiratory mechanics during one-lung ventilation. We therefore invesgate that the effect of humidified ventilation on oxygenation and respiratory mechanics during one-lung ventilation .

Detailed Description

Not available

Study Timeline

• Study Start: 2011-03
• Primary Completion: 2012-01
• Study Completion: 2012-04
• Status Verified: 2012-07
• Study First Submitted: 2012-07-05
• Study First Submitted QC: 2012-07-09
• Last Update Submitted: 2012-07-09
• Study First Posted: 2012-07-10
• Last Update Posted: 2012-07-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• ASA physical status class I,II
• Unilateral lung lobectomy
• Use of one-lung ventilation

Exclusion Criteria

• COPD
• CAOD
• Unstable cardiovascular status
• Peak inspiratory pressure > 30 mmHg

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Vaporizing humidifier	Vaporizing humidifier	Vaporizing humidifier applying during one-lung ventilation

Primary Outcome Measures

Name	Time	Method
arterial oxygenation	T1(10min before one-lung ventilation),T2(30min after one-lung ventilation),T3(60min), T4(10min after two lung ventilation)	T1,T2,T3,T4: all measurement in lateral position, T1-arterial oxygenation(PaO2), T2-arterial oxygenation(PaO2),T3-arterial oxygenation(PaO2),T4-arterial oxygenation(PaO2)

Secondary Outcome Measures

Name	Time	Method
Respiratory dynamic parameters	T1,T2,T3,T4 (same as 'primary outcome measure')	T1,T2,T3,T4: T1-respiratory dynamic parameters, T2-respiratory dynamic parameters, T3-respiratory dynamic parameters, T4-respiratory dynamic parameters

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of