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Clinical Trials/NCT02945709
NCT02945709
Completed
Not Applicable

Attention Control Treatment for Post Traumatic Stress Disorder

Tel Aviv University1 site in 1 country60 target enrollmentOctober 2016
ConditionsPTSD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
PTSD
Sponsor
Tel Aviv University
Enrollment
60
Locations
1
Primary Endpoint
A diagnosis of PTSD and a total score of severity symptoms, as driven from the CAPS-5 interview
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The purpose of this study is to explore the efficacy of Attention Control Training for Post Traumatic Stress Disorder (PTSD).

ACT was found to be effective in decreasing attention bias variability and PTSD symptoms in combat veterans (Badura-Brack, et al., 2015). It is now important to continue the examination of ACT's efficacy in additional populations of patients with PTSD. Such extension of treatment to other traumatic experiences raises the question of whether the threatening content of the training material could be personalized for each patient.

Detailed Description

The aim of this study is to explore the efficacy of Attention Control Training for Post Traumatic Stress Disorder (PTSD). ACT was found to be effective in decreasing attention bias variability and PTSD symptoms in combat veterans (Badura-Brack, et al., 2015). It is now important to continue the examination of ACT's efficacy in additional populations of patients with PTSD. Such extension of treatment to other traumatic experiences raises the question of whether the threatening content of the training material could be personalized for each patient. For this purpose, we will recruit participants that are diagnosed with PTSD and will be randomly assigned to one of three conditions: personalized ACT, non-personalized ACT, or control training We expect that personalized ACT will produce greater reduction in PTSD symptoms relative to a non-personalized ACT, and that both these conditions will be more effective in symptoms reduction than a control condition not designed to affect attention or expose patients to threat stimuli. We also expect the ACT conditions to reduce attention bias variability relative to the control condition.

Registry
clinicaltrials.gov
Start Date
October 2016
End Date
December 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yair Bar-Haim

Professor Yair Bar-Haim

Tel Aviv University

Eligibility Criteria

Inclusion Criteria

  • Meeting a current diagnosis of Post-Traumatic Stress Disorder (PTSD) according to DSM-V (American Psychiatric Association, 2013);

Exclusion Criteria

  • A diagnosis of psychotic or bipolar disorders.
  • A diagnosis of a neurological disorder (i.e., epilepsy, brain injury).
  • Suicidal ideation.
  • Drugs or alcohol abuse.
  • Non-fluent Hebrew.
  • A pharmacological treatment that is not stabilized in the past 3 months (a stable treatment will not be a reason for exclusion from the study).
  • Pregnancy. -

Outcomes

Primary Outcomes

A diagnosis of PTSD and a total score of severity symptoms, as driven from the CAPS-5 interview

Time Frame: 40 minutes

The Clinician Administered PTSD Scale (CAPS-5), is a structured interview that will be used to make a diagnosis of PTSD according to the DSM-V criteria. This interview is consists of 30 items regarding the frequency and intensity of PTSD symptoms and a total score of severity is been rated (Weathers, Blake, Schnurr, Kaloupek, Marx, \& Keane, 2013).

Secondary Outcomes

  • Total score of the PTSD Checklist (PCL-5).(10 minutes)

Study Sites (1)

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