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Clinical Trials/NCT03834844
NCT03834844
Active, Not Recruiting
N/A

Mindfulness Meditation and Patient Education for Symptom Management in Individuals With Atrial Fibrillation(AF): Do They Need to Be Offered Together?

Stanford University1 site in 1 country50 target enrollmentMay 1, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Paroxysmal Atrial Fibrillation
Sponsor
Stanford University
Enrollment
50
Locations
1
Primary Endpoint
Change from Baseline Atrial Fibrillation Symptom Burden and Symptom Severity Scores
Status
Active, Not Recruiting
Last Updated
last year

Overview

Brief Summary

The aim of this project is to determine whether the entire intervention (Mindfulness meditation, AF education, and weekly phone visits) that is nurse delivered to individuals with paroxysmal atrial fibrillation is more effective than a combination, single or no intervention in the reduction of overall AF symptoms, anxiety, and negative illness perception; or the improvement of quality of life (QOL) and functional status.

Registry
clinicaltrials.gov
Start Date
May 1, 2018
End Date
December 31, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Paul Wang

Professor of Medicine

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Individuals with Symptomatic Paroxysmal Atrial Fibrillation
  • A symptomatic episode of PAF within last 6 months
  • 18 years old or greater
  • Able to read and understand English
  • Able to participate in weekly phone calls
  • Able to attend two video visit/phone sessions that are 6 weeks apart

Exclusion Criteria

  • Diagnosed with low cardiac function (NYHA Class IV)
  • Life expectancy of less than 6 months
  • Hospitalized in prior 3 months for illness other than PAF
  • Previously practiced mindfulness
  • Cognitive impairment

Outcomes

Primary Outcomes

Change from Baseline Atrial Fibrillation Symptom Burden and Symptom Severity Scores

Time Frame: Baseline (Initial), 12 month

Atrial Fibrillation Burden and Symptom Severity will be calculated from the patient-completed responses on the Atrial Fibrillation Symptom Severity Scale-Symptom Burden can range from 3.25 (minimally bothersome) to 30 (continuous symptomatic episodes) and is based on event frequency (1-10), duration (1.25-10), and global episode (1-10). Symptom severity is based on symptom specific subscale with range from 0(no symptoms) to 35 (severe symptoms).

Change from Baseline in AF Quality of Life Score

Time Frame: Baseline (Initial), 12 month

Quality of Life will be assessed using a patient completed questionnaire, Atrial Fibrillation Effect on Quality of Life Questionnaire. The AFEQT score is a combined score of 21 items (21-100) with a higher score representing greater QOL.

Secondary Outcomes

  • Change from Baseline in Anxiety(Baseline (Initial), 12 months)

Study Sites (1)

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