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Protease activity on dysplastic leukoplakia sites

Conditions
Oral leukoplakia
Registration Number
NL-OMON23952
Lead Sponsor
Amsterdam UMC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
48
Inclusion Criteria

OL and OSCC groups (group A and B): all new patients (age ? 18 years) diagnosed with oral leukoplakia or OSCC at the Amsterdam UMC location VUmc
Control group (group C): Volunteers in the control group will be age and sex matched compared to the OL and OSCC groups. Healthy is defined as an American Society of Anesthetists score I and without medication use except for oral contraception and no OL and/or OSCC

Exclusion Criteria

Age < 18 years

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Protease activity in saliva and saliva biofilm
Secondary Outcome Measures
NameTimeMethod
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