Motor Response after Dorsal Root Ganglion Stimulation: A pilot study of 10 patients with Motor Complete Paraplegia.

Recruiting

• Conditions: Paraplegia; Spinal Cord Injury; 10041543

• Registration Number: NL-OMON47916
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- Paraplegia caused by trauma >2 years prior to inclusion
- Grade A or B neurological deficit on the ASIA Impairment scale
- Age >17 years
- Any Wounds (e.g. decubitus)

Exclusion Criteria

- Depression or an anxiety disorder
- Pregnancy
- Life expectancy < 1 year

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The aim of this case series is to investigate if DRG stimulation can evoke<br /><br>motor responses in the lower extremities in patients with motor complete spinal<br /><br>cord injury. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>In addition to motor response, we will try to investigate the following<br /><br>secondary objectives:<br /><br>- Weight-bearing ability (Non-assisted standing)<br /><br>- Assisted Standing<br /><br>- Muscle Strength (measured using a MicroFet 2 dynamometer and the MRC scale<br /><br>for muscle strength)<br /><br>- Voluntary movements<br /><br>- Patient Expectations of experimental treatment<br /><br>- Pain experience during stimulation</p><br>