assessment of serum GDNF level before/after treatment with HD- tDCS in bipolar affective disorder
Not Applicable
- Conditions
- Health Condition 1: F31- Bipolar disorderHealth Condition 2: F313- Bipolar disorder, current episodedepressed, mild or moderate severity
- Registration Number
- CTRI/2019/05/018949
- Lead Sponsor
- CENTRAL INSTITUTE OF PSYCHIATRY
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosis of bipolar affective disorder according to diagnostic criteria of research of ICD 10
Bipolar affective disorder current episode manic with or without psychotic symptoms
Age group between 18 to 45 yrs of age of either sex
Patients who is drug free or drug naive for a minimum of 8 weeks
Patients giving written informed consent
YMRS score of more than greatyer and equal to 10
Exclusion Criteria
Presence of comorbid neurological or other psychiatric disorder
History of epilepsy sustained brain damage or any neurological procedures
Subjects who have received ECT or rTMS in past 2 months
Developmental delay or mental retardation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome of the study is change in GDNF levels in patients with Bipolar Affective Disorder with improvement in mood states.Timepoint: At baseline ,before application of HDtdcs and after application of HDtdcs
- Secondary Outcome Measures
Name Time Method Secondary outcomes are changes in Psychopathology scores as measured by YMRS after application of HD-tDCS.Timepoint: At baseline, before application of HDtdcs and after application of HDtdcs