The Effect of Time on the Outcome of Periodontal Treatment.
- Conditions
- Periodontitis
- Interventions
- Procedure: Periodontal treatment
- Registration Number
- NCT05643287
- Lead Sponsor
- 251 Hellenic Air Force & VA General Hospital
- Brief Summary
Re-evaluation after non-surgical periodontal treatment remains an integral part of comprehensive periodontal therapy. This re-evaluation determines if a patient is in need either of surgical periodontal therapy or a personalized program of supportive periodontal treatment. However important, this time point is yet to be determined.This interventional study aims to clarify which is the best time to re-evaluate the therapeutic result after non-surgical periodontal treatment.
- Detailed Description
This randomized clinical trial aims to clarify which is the best time to re-evaluate the therapeutic result after non-surgical periodontal treatment. For this purpose the participants will be recruited among people who come to the Periodontal Department of 251 Hellenic Air Force Hospital for periodontal treatment. Each participant is going to submit informed consent in order to be included in the study. Patients with the diagnosis of Periodontitis will be submitted to non-surgical periodontal treatment with ultrasonic and manual scalers within two sessions, under local anaesthesia. The result of the treatment is going to be evaluated at 6, 12 and 24 weeks after treatment completion.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 75
- Systematically healthy adults
- Informed consent form completion
- Periodontitis Diagnosis
- Patients not having received periodontal treatment since 12 months before
- Medical History that interferes with wound healing
- Antibiotic and anti-inflammatory drugs intake
- Medication that induces gingival enlargement
- Pregnancy/ Lactation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Periodontitis patients Periodontal treatment Periodontitis patients receiving non-surgical periodontal treatment.
- Primary Outcome Measures
Name Time Method Probing Pocket Depth 1 6 weeks after periodontal treatment The distance between the gingival margin and the base of the sulcus/pocket
Probing Pocket Depth 2 12 weeks after periodontal treatment The distance between the gingival margin and the base of the sulcus/pocket
Probing Pocket Depth 3 24 weeks after periodontal treatment The distance between the gingival margin and the base of the sulcus/pocket
Probing Pocket Depth 0 Baseline The distance between the gingival margin and the base of the sulcus/pocket
- Secondary Outcome Measures
Name Time Method Furcation involvement Baseline, 6, 12, 24 weeks after treatment Presence or absence of furcation involvement and degree of furcation defect
matrix metalloproteinase Baseline, 6, 12, 24 weeks after treatment matrix metalloproteinase 8 levels in whole saliva
Clinical attachment level Baseline, 6, 12, 24 weeks after treatment The distance between cementoenamel junction and the base of the sulcus/pocket
Plaque Index Baseline, 6, 12, 24 weeks after treatment Number of sites with presence of dental plaque/ total number of sites
Bleeding on Probing Baseline, 6, 12, 24 weeks after treatment Number of sites with presence of bleeding/total number of sites
Oral Health Impact Profile (OHIP)-14 Questionnaire Baseline, 6, 12, 24 weeks after treatment Questionnaire
Tooth Mobility Baseline, 6, 12, 24 weeks after treatment degree of tooth mobility