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Clinical Trials/NCT05643287
NCT05643287
Not yet recruiting
Not Applicable

The Effect of Time on the Outcome of Periodontal Treatment.

251 Hellenic Air Force & VA General Hospital0 sites75 target enrollmentFebruary 3, 2025
ConditionsPeriodontitis

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Periodontitis
Sponsor
251 Hellenic Air Force & VA General Hospital
Enrollment
75
Primary Endpoint
Probing Pocket Depth 2
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

Re-evaluation after non-surgical periodontal treatment remains an integral part of comprehensive periodontal therapy. This re-evaluation determines if a patient is in need either of surgical periodontal therapy or a personalized program of supportive periodontal treatment. However important, this time point is yet to be determined.This interventional study aims to clarify which is the best time to re-evaluate the therapeutic result after non-surgical periodontal treatment.

Detailed Description

This randomized clinical trial aims to clarify which is the best time to re-evaluate the therapeutic result after non-surgical periodontal treatment. For this purpose the participants will be recruited among people who come to the Periodontal Department of 251 Hellenic Air Force Hospital for periodontal treatment. Each participant is going to submit informed consent in order to be included in the study. Patients with the diagnosis of Periodontitis will be submitted to non-surgical periodontal treatment with ultrasonic and manual scalers within two sessions, under local anaesthesia. The result of the treatment is going to be evaluated at 6, 12 and 24 weeks after treatment completion.

Registry
clinicaltrials.gov
Start Date
February 3, 2025
End Date
December 2025
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
251 Hellenic Air Force & VA General Hospital
Responsible Party
Principal Investigator
Principal Investigator

Georgia Malamoudi

Attendant at Periodontology Department of 251 Hellenic Air Force & VA Hospital

251 Hellenic Air Force & VA General Hospital

Eligibility Criteria

Inclusion Criteria

  • Systematically healthy adults
  • Informed consent form completion
  • Periodontitis Diagnosis
  • Patients not having received periodontal treatment since 12 months before

Exclusion Criteria

  • Medical History that interferes with wound healing
  • Antibiotic and anti-inflammatory drugs intake
  • Medication that induces gingival enlargement
  • Pregnancy/ Lactation

Outcomes

Primary Outcomes

Probing Pocket Depth 2

Time Frame: 12 weeks after periodontal treatment

The distance between the gingival margin and the base of the sulcus/pocket

Probing Pocket Depth 1

Time Frame: 6 weeks after periodontal treatment

The distance between the gingival margin and the base of the sulcus/pocket

Probing Pocket Depth 3

Time Frame: 24 weeks after periodontal treatment

The distance between the gingival margin and the base of the sulcus/pocket

Probing Pocket Depth 0

Time Frame: Baseline

The distance between the gingival margin and the base of the sulcus/pocket

Secondary Outcomes

  • Furcation involvement(Baseline, 6, 12, 24 weeks after treatment)
  • matrix metalloproteinase(Baseline, 6, 12, 24 weeks after treatment)
  • Clinical attachment level(Baseline, 6, 12, 24 weeks after treatment)
  • Plaque Index(Baseline, 6, 12, 24 weeks after treatment)
  • Bleeding on Probing(Baseline, 6, 12, 24 weeks after treatment)
  • Oral Health Impact Profile (OHIP)-14 Questionnaire(Baseline, 6, 12, 24 weeks after treatment)
  • Tooth Mobility(Baseline, 6, 12, 24 weeks after treatment)

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