Comparison of Resistive Breathing Versus Inspiratory Hold Technique in Patients With Chronic Bronchitis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- oxygen saturation
研究概览
简要总结
The aim of the study is to determine the importance and impact of resistive breathing techniques versus inspiratory hold techniques in patients with chronic bronchitis and specially to find out if there are any changes seen in results measured via the incentive spirometer.
详细描述
Chronic Bronchitis (CB) is defined as a chronic cough and sputum production for at least 3 months a year for 2 consecutive years. It is covered under the umbrella term of Chronic Obstructive Pulmonary Disease (COPD). Chronic bronchitis is thought to be caused by overproduction and hypersecretion of mucus by goblet cells. Epithelial cells lining the airway response to toxic, infectious stimuli by releasing inflammatory mediators and e.g. pro-inflammatory cytokines. During an acute exacerbation of chronic bronchitis, the bronchial mucous membrane becomes hyperemic and edematous with diminished bronchial mucociliary function. This, in turn, leads to airflow impediment because of
luminal obstruction to small airways. The airways become clogged by debris and this further increases the irritation. The characteristic cough of bronchitis is caused by the copious secretion of mucus in chronic bronchitis. Pseudostratified epithelium, highlighting the pseudostratified epithelial cells, goblets cells (shown in blue), then underlying connective tissue.(3) To determine the importance and impact of resistive breathing techniques versus inspiratory hold techniques in patients with chronic bronchitis and specially to find out if there are any changes seen in results measured via incentive spirometer. There are few studies done over it whereas purpose of this research work is to compare these techniques to get better results.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Diagnosed with chronic bronchitis
- •Clinically stable patients.
- •Both genders.
- •Age 45 to 60 years.
- •Pink puffers included in this study
- •Clients that are involved in research are not allowed for other interventional therapies. They can take their regular medications.
- •Patients diagnosed at least 2 years ago with bronchitis.
排除标准
- •• Presence of any genetic disorders (cystic fibrosis).
- •Recent spinal / chest surgery
- •Cardiac issues
- •Fractures of vertebra caused by osteoporosis.
结局指标
主要结局
oxygen saturation
时间窗: Changes will be assessed at baseline, 3rd week and 6th weeks measured
amount of oxygen traveling through your body with your red blood cells. Changes will be assessed at baseline, 3rd week and 6th weeks measured
Forced expiratory volume in one second
时间窗: Changes will be assessed at baseline, 3rd week and 6th weeks measured
amount of air expired in first one second. Changes will be assessed at baseline, 3rd week and 6th weeks measured
shortness of breath measured through borge scale of dyspnea
时间窗: Changes will be assessed at baseline, 3rd week and 6th weeks measured
shortness of breath. Changes will be assessed at baseline, 3rd week and 6th weeks measured
Forced vital capacity
时间窗: Changes will be assessed at baseline, 3rd week and 6th weeks measured
the total amount of air exhaled during the FEV test. Changes will be assessed at baseline, 3rd week and 6th weeks measured
SGRQ questionnaire
时间窗: Changes will be assessed at baseline, 3rd week and 6th weeks measured
how breathing problems effects quality of life . Changes will be assessed at baseline, 3rd week and 6th weeks measured
FEV1/FVC ratio
时间窗: 6 weeks
the amount of air exhaled in the first second divided by all of the air exhaled during a maximal exhalation.
次要结局
未报告次要终点
