Cognitive impairment following cardiac arrest and Target Temperature Management (A sub-study of the TTM Trial) - Cognitive impairment following cardiac arrest

Academisch Medisch Centrum0 个研究点目标入组 85 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•1. TTM study patients who are alive at six-month follow-up and give consent to the cognitive sub-study
•2. Informants (usually a relative or close friend/caregiver) of the patient above (1) who give consent to the cognitive sub-study
•3. STEMI patients at the given centre, the sex-matched patient who best fits in age to the TMM patient above (1) with a similar date of infarct who gives consent to the cognitive sub-study
•4. Informants (usually a relative or close friend/caregiver) of 3 above who give consent to participate.

•The same exclusion criteria as for the main TTM study with the addition that control patients should not have a history of cardiac arrest.
•Exclusion criteria TTM study: Conscious patients, pregnancy, out-of-hospital cardiac arrest of presumed non-cardiac cause, cardiac arrest after arrival in hospital, known bleeding diathesis, suspected or confirmed acute intracranial bleeding, suspected or confirmed acute stroke, temperature on admission <30°C, unwitnessed asystole, persistent cardiogenic shock, known limitations in therapy, known disease making 180 day survival unlikely, known pre-arrest cerebral performance category 3 or 4, >240 minutes from ROSC to randomisation, no informed consent.

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