NL-OMON42968
已完成
不适用
euroinflammation in cognitive decline post-cardiac surgery: The FOCUS study - The FOCUS study
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- postoperative cerebral dysfunction
- 发起方
- Radboud Universitair Medisch Centrum
- 入组人数
- 40
- 状态
- 已完成
- 最后更新
- 2年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Planned for coronary artery bypass grafting surgery (CABG)
- •Age \> 50 years
- •High\-affinity or mixed affinity binders based on rs6971 polymorphism for TSPO
排除标准
- •\- Patients with cognitive disorders that have not recovered enough to be able to understand the study leaflets and information for participation.
- •\- Pregnancy or wish to become pregnant within 2 weeks after PET\-CT scan
- •\- Contra\-indication to undergo a PET/CT or MRI scan, including claustrophobia.
- •\- Patients who undergo a combination of CABG surgery and additional valve surgery.
- •\- Previous cardiac surgery.
- •\- Low\-affinity binder based on rs6971 polymorphism for TSPO, or unable to determine rs6971 polymorphism.
- •\- Brain or spinal surgery within the last 6 months.
- •\- Meningitis or brain infection within the last 6 months.
- •\- Pre\-existing dementia or neurodegenerative disease or cognitive impairment interfering with the ability to understand informational material about this research project.
- •\- Presence of a CSF catheter or shunt.
结局指标
主要结局
未指定
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进行中（未招募）
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