EUCTR2016-002016-40-NL
进行中（未招募）
1 期
euroinflammation in cognitive decline post-cardiac surgery: the FOCUS study - The FOCUS study
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- Radboudumc
- 状态
- 进行中（未招募）
- 最后更新
- 9年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •Patients planned for coronary artery bypass grafting surgery (CABG)
- •Age \> 50 years
- •High\-affinity binders or mixed\-affinity binders based on rs6971 polymorphism for TSPO
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 10
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range 30
排除标准
- •\-Patients with cognitive disorders that have not recovered enough to be able to understand the study leaflets and information for participation.
- •\-Pregnancy or wish to become pregnant within 2 weeks after PET\-CT scan
- •\-Contra\-indication to undergo a PET/CT or MRI scan, including claustrophobia.
- •\-Patients who undergo a combination of CABG surgery and additional valve surgery.
- •\-Previous cardiac surgery.
- •\-Low\-affinity binder based on rs6971 polymorphism for TSPO, or unable to determine rs6971 polymorphism.
- •\-Brain or spinal surgery within the last 6 months.
- •\-Meningitis or brain infection within the last 6 months.
- •\-Pre\-existing dementia or neurodegenerative disease or cognitive impairment interfering with the ability to understand informational material about this research project.
- •\-Presence of a CSF catheter or shunt.
结局指标
主要结局
未指定
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