Outcomes of two-stage liver resection in the treatment of a rare type of primary liver cancer

Not Applicable

Completed

• Conditions: Cholangiocarcinoma; Cancer; Intrahepatic bile duct carcinoma

• Registration Number: ISRCTN10972467
• Lead Sponsor: Chirurgische Universitätsklinik Heidelberg

Brief Summary

2023 Results article in https://pubmed.ncbi.nlm.nih.gov/36959071/ (added 31/05/2023) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/38067316/ (added 04/07/2024)

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-01-01
• Study Start: 2022-06-16
• Last Update Posted: 15 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with cholangiocarcinoma undergoing the ALPPS procedure

Exclusion Criteria

Does not meet the inclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative morbidities classified as grade I to V based on the Clavien–Dindo classification during the hospital stay

Secondary Outcome Measures

Name	Time	Method
1. Post-hepatectomy liver failure (PHLF) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period<br>2. Post-hepatectomy bile leakage (PHBL) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period<br>3. Post-hepatectomy liver hemorrhage (PHH) evaluated using the definition provided by the international study group of liver surgery (ISGLS), and classified respectively according to severity grade, during the 90-day postoperative period