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Comparison of postoperative liver function between total intravenous anesthesia and inhalation anesthesia in patients with preoperatively elevated liver transaminase levels: a single-center retrospective cohort study

Not Applicable
Conditions
Patients with preoperatively elevated liver transaminase levels who underwent surgery under general anesthesiaanesthesia
Registration Number
JPRN-UMIN000038949
Lead Sponsor
Department of Anesthesiology and Pain Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
Brief Summary

In 730 patients (TIVA: n=138; INHA: n=592), postoperative AST and ALT changes were significantly lower in the TIVA group than in the INHA group. After 1:4 propensity score matching (TIVA: n=94; INHA: n=376), only the ALT change was significantly lower after TIVA than after INHA.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
730
Inclusion Criteria

Not provided

Exclusion Criteria

patients with normal range of preoperative LFT results, hepatic surgery,heart surgery and Cesarean section

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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