Caries Prevention Potential of Pearl Powder Versus Casein Phosphopeptide-amorphous Calcium Phosphate on Enamel White Spot Lesions: Randomized Clinical Trial.
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 58
- 主要终点
- caries prevention in enamel white spot lesion
研究概览
简要总结
to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel white spot lesions.
详细描述
The aim of the study is to evaluate the caries prevention potential of pearl powder against CPP-ACP in enamel White Spot Lesions using laser fluorescence device scoring from 0 to 99, with daily application time of 3 months and follow up period of 6,9,and 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 12 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •good oral hygiene
- •cooperative patient
- •completion of orthodontic therapy
- •presence of at least two white spot lesions on the labial surface of six maxillary anterior teeth, that were not present before orthodontic treatment
排除标准
- •bad oral hygiene
- •lack of patients compliance
- •allergy to milk products
- •pregnant or lactating women
- •presence of dentin caries, restorations, or enamel hypoplasia on maxillary anterior teeth
- •presence of periodontal pockets around maxillary anterior teeth
研究组 & 干预措施
pearl powder
natural product, support bone and joint health
干预措施: pearl powder (Other)
CPP-ACP
product for professional use containing the active ingredient (CPP-ACP), a special milk-derived protein that has a unique ability to release bio-available calcium and phosphate to tooth surfaces.
干预措施: CPP-ACP (Drug)
结局指标
主要结局
caries prevention in enamel white spot lesion
时间窗: 12 months
caries prevention using laser fluorescence device
次要结局
未报告次要终点
研究者
Ruba Alaa El Din Adel El Damarisy
principal investigator
Cairo University