A Prospective, Randomized Clinical Study on the Effects of Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) Paste on Plaque, Gingivitis and White Spot Lesions in Orthodontic Patients - Part 2
Not Applicable
Completed
- Conditions
- Early Caries Lesions
- Registration Number
- NCT00670618
- Lead Sponsor
- University Hospital, Ghent
- Brief Summary
Influence of CPP-ACP paste and Elmex Medical Gel on the prevention of white spot lesions in orthodontic patients during fixed appliances.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 325
Inclusion Criteria
- No white spot lesion at the time of placement of fixed appliances
Exclusion Criteria
- White spots already present before start orthodontic treatment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Prevention of the opacity of white spots during orthodontic treatment with fixed appliances After 2 years
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie CPP-ACP's remineralization effects on early caries lesions in orthodontic patients?
How does CPP-ACP paste compare to fluoride-based gels in preventing white spot lesions during orthodontic treatment?
Are there specific biomarkers that predict orthodontic patients' response to CPP-ACP in caries prevention?
What adverse events are associated with CPP-ACP application in high-risk caries populations and how are they managed?
What combination therapies with CPP-ACP show enhanced efficacy in managing demineralization around fixed orthodontic appliances?
Trial Locations
- Locations (1)
University Hospital Ghent
🇧🇪Ghent, Belgium
University Hospital Ghent🇧🇪Ghent, Belgium