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Clinical Trials/NCT03214432
NCT03214432
Completed
Not Applicable

Return to Work After Mild Traumatic Brain Injury

University of Copenhagen1 site in 1 country38,372 target enrollmentJuly 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Mild Traumatic Brain Injury
Sponsor
University of Copenhagen
Enrollment
38372
Locations
1
Primary Endpoint
nRTW
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Background:

Patients with mild traumatic brain injury can to some extend experience long-term physical, cognitive, social and behavioral deficits, which have serious implications for employment trajectories and financial independence. These deficits have shown to be more pronounced in women. High socio-economic position such as income, level of education and employment status before the accident have shown to affect return to work. But also cohabitation status, ethnicity and health are important factors. Previously studies are typically self-report studies, and are often small and may suffer from selection bias due to patient nonresponse.

Aim:

The aim of this study is to describe no return to work among patients with mild traumatic brain injury in Denmark and to examine how factors such as age, gender, cohabitation status, socio-economic and pre-injury health factors affect no return to work up to 5 years post-injury.

Hypothesis:

We hypothesize that most patients with mild traumatic brain injury return to work within work 6 months post-injury, and that patients with mild traumatic brain injury injury receive more social transfer payments compared to the general population.

Additionally, we hypothesize that low socio economic position, comorbidities and being single are associated with prolonged no return to work.

Methods:

The present study is an observational national register-based cohort study with long-term follow up of patients with mild traumatic brain injury from 1st of January 2008 - 31st of December 2012 in Denmark. Patients aged 18-60 years diagnosed with concussion from 1st of January 2003-31st of December 2007 in the national patient register will be included in the study. Data will be retrieved from several national databases, including the DREAM database containing data on social benefits and reimbursements.

Primary outcome is no-return to work (nRTW) due to any cause and the following four secondary outcomes are graded and should be regarded as a continuum ranging from health related nRTW, limited nRTW, permanently nRTW and mortality.

The results will be published as two separate scientific articles.

Registry
clinicaltrials.gov
Start Date
July 1, 2017
End Date
July 4, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Heidi Jeannet Graff

Ph.d. student

University of Copenhagen

Eligibility Criteria

Inclusion Criteria

  • ICD-10 code for concussion as action diagnosis (ICD-10: S06.0)
  • Working age adults between 18-60 years old at the time of injury
  • Gainfully occupied or deemed available for work the week preceding the time of injury

Exclusion Criteria

  • Patients were excluded if they were hospital treated and diagnosed with other major neurological injuries such as spinal cord and column injuries and traumatic brain injuries (TBI) besides the concussion at baseline.
  • Patients were excluded, who 5 years prior to baseline (1st of January 1998 - 31st of December 2002) had sustained major neurological impairments including concussions.
  • Patients outside of the age limit
  • Patients not resident in Denmark
  • Patients on unemployment benefits and not economically active at the time of injury

Outcomes

Primary Outcomes

nRTW

Time Frame: 5 years follow up

No-return to work up to 5 years post-injury. nRTW is defined as receiving social transfer payments in any given week during the follow-up period. If no social benefit is given in the DREAM register, it is assumed the patient is gainfully occupied or self-supporting.

Secondary Outcomes

  • Health related nRTW(5 years follow up)
  • Mortality(5 years follow up)
  • Limited nRTW(5 years follow up)
  • Permanently nRTW(5 years follow up)

Study Sites (1)

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