Perioperative Epidural Trial (POET) Pilot Study

Not Applicable

Completed

• Conditions: Post Operative Pain Control

• Registration Number: NCT00221260
• Lead Sponsor: University of British Columbia

Brief Summary

To investigate if the use of perioperative neuraxial blockade reduces post-operative mortality and cardiorespiratory events compared to intraoperative general anesthesia AND postoperative IV narcotic analgesia. This is a feasibility study to determine if recruitment and execution of the protocol could be done in a timely manner in a much larger trial

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09
• Study First Submitted: 2005-09-18
• Study First Submitted QC: 2005-09-18
• Study First Posted: 2005-09-22
• Primary Completion: 2008-01
• Study Completion: 2008-01
• Status Verified: 2008-09
• Last Update Submitted: 2008-09-24
• Last Update Posted: 2008-09-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Subjects at high risk of cardio-respiratory complications post operatively.

Exclusion Criteria

Contraindication to epidural anesthesia

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Combined mortality, MI, cardiac arrest, post operative pneumonia , and respiratory failure

Secondary Outcome Measures

Name	Time	Method
DVT, pulmonary embolism, TIA, CVA, CHF, clinically significant bradycardia/hypotension

Trial Locations

Locations (1)

Vancouver General Hospital, Clinical Health Research Unit; 🇨🇦 Vancouver, British Columbia, Canada