Efficacy of Epidural Analgesia Initiated in the Preoperative Period in Lower Extremity Osteosarcoma
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Osteosarcoma
- Sponsor
- Istanbul University
- Enrollment
- 28
- Locations
- 1
- Primary Endpoint
- Opioid consumption
- Last Updated
- 4 years ago
Overview
Brief Summary
In this study, the investigators aim to reduce complications in orthopedic malignancy surgeries and to increase the quality of life of patients who will be operated on.
Detailed Description
In the preoperative period, the participants will be taken to the block room. The participants will be monitored, standard sedation will be applied. Patients in the first group will be provided with preoperative and peroperative analgesia with an epidural catheter. The second group patient will be get no block. Afterwards, both groups will be operated under similar general anesthesia conditions. A patient-controlled analgesia device will be attached to each group of participants and their postoperative follow-up will be made.
Investigators
Nur Canbolat
Principle Invastigator, M.D.
Istanbul University
Eligibility Criteria
Inclusion Criteria
- •accepting the study protocol,
- •age older than 18 years and younger than 80 years,
- •undergoing lower extremity osteosarcoma surgery
- •the American Society of Anesthesiologist (ASA) physical status of I-II-III
Exclusion Criteria
- •infection at the injection site
- •coagulation disorder
- •patients with central nervous system related disease
- •septic patients
Outcomes
Primary Outcomes
Opioid consumption
Time Frame: 48 hours
miligram
Measurement of postoperative pain
Time Frame: 48 hours
VAS (visual analog scale) (0: no pain, 10: the worst pain imaginable)
Secondary Outcomes
- Beck Depression Inventory (BDI)(Will be done 2 times 1- on pre-operative hospitalization 2- in the 1st month follow-up after surgery])
- Amount of peroperative bleeding(During surgery)
- Amount of postoperative bleeding(48 Hours)
- Patient satisfaction(Will be done 3 times 1- a day after surgery 2- in the 1st week follow up after surgery 3- in the 1st month follow-up after surgery)
- Postoperative complications(postoperative period up to 3 days)
- Intensive care unit stay(48 hours)
- Hospital stay(72 hours)