To rescue cognition in schizophrenia with valaciclovir: a focus on hippocampal inflammatio

Completed

• Conditions: psychiatric disorder; schizophrenia; 10039628

• Registration Number: NL-OMON38222
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

-Age above 18
-Written informed consent for participation
-Diagnosis: schizophrenia, all subtypes
-Psychosis

Exclusion Criteria

-Pregnancy, or presumption of pregnancy
-The use of benzodiazepines
-The use of NSAID or paracetamol in week before the PET scans and during the treatment of valaciclovir
-Use of somatic medication which may affect the immune system
-Use of any investigational drug
-Current or recent (<1 year) alcohol or substance abuse
-Disturbed kidney function and/or liver function
-Current or recent (<4 weeks) infectious or inflammatory disease
-Participation in a scientific research study (<1 year) involving radiation
-Claustrophobia
-Presence of materials in the body that can be magnetized

Study & Design

• Study Type: Interventional
• Study Design: Not specified