Validation of Kinocardiography, New Technology for Cardiac Linear and Torsional Contractility Measurement, to Assess Heart Failure Patient With Low Ejection Fraction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Impaired Left Ventricular Ejection Fraction
- Sponsor
- Brugmann University Hospital
- Enrollment
- 130
- Locations
- 1
- Primary Endpoint
- Total heart kinetic energy
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Measuring cardiac contractility is commonly realized with gold standard echocardiography or MRI. Portable devices to measure this contractility are not available as for rhythm and electric function assessment. The new Kinocardiography technology could provide a non invasive and portable tool to measure contractility.
This device records the electric and mechanic function of the heart simultaneously. With electrodes and adequate electronics, ECG is recorded. 6 degrees of freedom accelerometers are also included in the device to measure the micro accelerations of the body at the body surface when the device is placed on the skin. Using physics principles and adequate calibration, those accelerations allow the investigators to calculate parameters such as kinetics energies related to cardiac contractility. Kinocardiography is a non invasive and portable technology.
Investigators
Dr Marielle Morissens
MD
Brugmann University Hospital
Eligibility Criteria
Inclusion Criteria
- •Control group: Left Ventricle Ejection Fraction ≥ 50 %
- •Heart failure patients: Left Ventricle Ejection Fraction \< 50 %
Exclusion Criteria
- •Intracardiac devices and arrhythmia at the time of assessment
- •Participates in other clinical study or trial.
Outcomes
Primary Outcomes
Total heart kinetic energy
Time Frame: 1 hour
Computed according to the micro accelerations of the body at the body surface. The hypothesis is that the investigators will observe a lower total heart kinetic energy for the group with impaired left ventricular ejection fraction in comparison to a paired control patient group.
Secondary Outcomes
- Ratio of torsional kinetic energy over total kinetic energy(1 hour)