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Clinical Trials/NCT03157115
NCT03157115
Completed
Not Applicable

Validation of Kinocardiography, New Technology for Cardiac Linear and Torsional Contractility Measurement, to Assess Heart Failure Patient With Low Ejection Fraction

Brugmann University Hospital1 site in 1 country130 target enrollmentJuly 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Impaired Left Ventricular Ejection Fraction
Sponsor
Brugmann University Hospital
Enrollment
130
Locations
1
Primary Endpoint
Total heart kinetic energy
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Measuring cardiac contractility is commonly realized with gold standard echocardiography or MRI. Portable devices to measure this contractility are not available as for rhythm and electric function assessment. The new Kinocardiography technology could provide a non invasive and portable tool to measure contractility.

This device records the electric and mechanic function of the heart simultaneously. With electrodes and adequate electronics, ECG is recorded. 6 degrees of freedom accelerometers are also included in the device to measure the micro accelerations of the body at the body surface when the device is placed on the skin. Using physics principles and adequate calibration, those accelerations allow the investigators to calculate parameters such as kinetics energies related to cardiac contractility. Kinocardiography is a non invasive and portable technology.

Registry
clinicaltrials.gov
Start Date
July 1, 2017
End Date
April 18, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr Marielle Morissens

MD

Brugmann University Hospital

Eligibility Criteria

Inclusion Criteria

  • Control group: Left Ventricle Ejection Fraction ≥ 50 %
  • Heart failure patients: Left Ventricle Ejection Fraction \< 50 %

Exclusion Criteria

  • Intracardiac devices and arrhythmia at the time of assessment
  • Participates in other clinical study or trial.

Outcomes

Primary Outcomes

Total heart kinetic energy

Time Frame: 1 hour

Computed according to the micro accelerations of the body at the body surface. The hypothesis is that the investigators will observe a lower total heart kinetic energy for the group with impaired left ventricular ejection fraction in comparison to a paired control patient group.

Secondary Outcomes

  • Ratio of torsional kinetic energy over total kinetic energy(1 hour)

Study Sites (1)

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