KINO-DYSPNEA: Validation of Kinocardiography to Distinguish Dyspnea of Cardiac Origin From Others
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 528
- 试验地点
- 1
- 主要终点
- Evaluate the ability of the Kinocardiography technique to discriminate cardiac caused dyspnea from others.
研究概览
简要总结
Seismocardiography (SCG) measures the thoracic vibrations caused by the cardiac contraction and ejection of blood into the great vessels. Current smartphones with gyroscopes and accelerometers can measure these vibrations. Based on these components we measure and quantify the cardiac kinetic energy (kinocardiography) in order to differentiate dyspnea of cardiac origin from dyspnea of other origin. The study is conducted in an emergency service where a smartphone performs the measurement during 3 minutes. The results of the kinocardiography-based classification are then compared to the final diagnosis made by a physician. Currently, 235 patients have been included in the clinical study since May 2022. This rapid and non-invasive measurement allows the aid-to-diagnosis of heart failure without being influenced by other factors like the renal function for example that can be NT-pro BNP blood marker.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged above 18 years old.
排除标准
- •Patients younger than 18 years old.
结局指标
主要结局
Evaluate the ability of the Kinocardiography technique to discriminate cardiac caused dyspnea from others.
时间窗: 18 months
Area under the receiver operating characteristic curve (AUROC), negative predictive value (NPV) and specificity, with two-sided 95% CIs.
次要结局
- Open retrospective exploratory study to validate the physiological interpretation of Kinocardiography in a clinical environment.(18 months)