Post-operative Analgesia Efficacy Using Ultrasound-guided Transmuscular Quadratus Lumborum Block Versus Ultrasound-guided Quadratus Lumborum Type II Block.

Phase 4

• Conditions: Nerve Block
• Interventions: Drug: Bupivacaine; Device: Ultrasound

• Registration Number: NCT03100994
• Lead Sponsor: Tri-Service General Hospital

Brief Summary

Post-operative analgesia efficacy using ultrasound-guided transmuscular quadratus lumborum block versus ultrasound-guided quadratus lumborum type II block

Detailed Description

The Quadratus Lumborum (QL) Block is an ultrasound-guided technique described by Rafael Blanco in 2007. The nerves to the lower abdominal wall can be anesthetized by injecting local anesthetics between the quadratus lumborum muscle and latissimus dorsi muscle, which is called quadratus lumborum type II block. 〝 Transmuscular quadratus lumborum block demonstrates that injectate spreads over the posterior abdominal wall to the psoas major muscle and includes the upper branches of the lumbar plexus.〞described by Adhikary in 2016. However there are no published reports comparing the 2 techniques. In our study, compared of ultrasound-guided QL2-blocks with transmuscular quadratus lumborum block to investigate analgesic consumption, pain level, opioid related side effects and mobilization.

Study Timeline

• Status Verified: 2017-03
• Study First Submitted: 2017-03-24
• Study Start: 2017-03-28
• Study First Submitted QC: 2017-03-29
• Last Update Submitted: 2017-03-29
• Study First Posted: 2017-04-04
• Last Update Posted: 2017-04-04
• Primary Completion: 2018-07
• Study Completion: 2018-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

• American Society of Anesthesiologists classification (ASA) 1~3
• adequate communication skills
• Body mass index < 32

Exclusion Criteria

chronic pain neurological illness/ neuropathy contraindication against local anesthetics

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Group B	Bupivacaine	Ultrasound guided transmuscular quadratus lumborum block with 0.125% bupivacaine 30ml
Group C	Ultrasound	Ultrasound guided quadratus lumborum type 2 block with 0.125% bupivacaine 30ml
Group B	Ultrasound	Ultrasound guided transmuscular quadratus lumborum block with 0.125% bupivacaine 30ml
Group C	Bupivacaine	Ultrasound guided quadratus lumborum type 2 block with 0.125% bupivacaine 30ml

Primary Outcome Measures

Name	Time	Method
morphine consumption	48 hours	morphine consumption

Secondary Outcome Measures

Name	Time	Method
Nausea or vomiting	48 hours	Severity of nausea or vomiting in the first 48 hours after surgery. Severe :3 Moderate:2 Mild:1 None: 0
Skin itch	48 hours	Severity of skin itch in the first 48 hours after surgery. Severe :3 Moderate:2 Mild:1 None: 0
Severity of postoperative pain via visual analogue pain scale (VAS)	48 hours	Total cumulative morphine dose in mg used in the first 48 hours after surgery
time to mobilization	48 hours	Time to mobile in the first 48 hours after surgery

Trial Locations

Locations (1)

Tri-Service General Hospital; 🇨🇳 Taipei, Taiwan