Curarisation and Intubation Conditions During Videolaryngoscopy With Glidescope Titanium

Phase 4

Completed

• Conditions: Tracheal Intubation
• Interventions: Drug: saline isotonic solution; Drug: Curare (Atracurium)

• Registration Number: NCT02404142
• Lead Sponsor: CHU de Reims

Brief Summary

In this prospective, randomized study, the investigators assess the intubation conditions during videolaryngoscopy with Glidescope Titanium whether patients receive (curare (Atracurium) group) or no (control group) within elective surgery patients with no difficult intubation prediction

Detailed Description

In this prospective, randomized study, the investigators assess the intubation conditions during videolaryngoscopy with Glidescope Titanium whether patients receive (curare (Atracurium)group) or no (control group) within elective surgery patients with no difficult intubation prediction. The IDS score assessed by an anesthesiologist from the video-recording is the primary outcome. All general anesthesias are standardized using Target Control Infusion of propofol and sufentanil. The investigators also compare IDS scores as assessed by intubators, time for tracheal intubation, and laryngeal morbidity in both groups.

Study Timeline

• Study Start: 2015-02-20
• Study First Submitted: 2015-03-17
• Study First Submitted QC: 2015-03-30
• Study First Posted: 2015-03-31
• Primary Completion: 2016-04-05
• Study Completion: 2016-08-05
• Status Verified: 2018-01
• Last Update Submitted: 2018-01-08
• Last Update Posted: 2018-01-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Elective Surgery Adult Patients
• no difficult intubation prediction

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group (saline isotonic solution)	saline isotonic solution	saline isotonic solution
Curar (Atracurium) group	Curare (Atracurium)	Curar (Atracurium)

Primary Outcome Measures

Name	Time	Method
IDS score video-assessed as described by Adnet et al. Measurement will be made by 2 experts anesthesiologists for centralized reading	Assessment will be done at the end of the inclusions period (9 months)	Number of IDS scores \<2 are compared

Secondary Outcome Measures

Name	Time	Method
IDS score assesed by the intubator anesthesiologist	3 days post intubation

Trial Locations

Locations (1)

Chu de Reims; 🇫🇷 Reims, France