Study of the expression of genes involved in the process of death in oocytes in four groups of patients undergoing ovulation stimulation cycle with four therapies.

Phase 2

Recruiting

• Conditions: Female Infertility.; N97.0; Female infertility associated with anovulation

• Registration Number: IRCT20101115005181N16
• Lead Sponsor: Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 15 June 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

The age of 20- 30 years old.
Normal response to induction of ovulation.

Exclusion Criteria

unexplained infertility Cause
Azoospermia
Ovarian hyper stimulation Syndrome

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Maturation of Oocyte. Timepoint: 36 hours after the last administration of treatment. Method of measurement: Electronic Microscope.;Fertilization rate. Timepoint: 24 hours after intra cytoplasmic sperm injection. Method of measurement: Electronic Microscope.;Rate of Embryo development. Timepoint: The third day of intra cytoplasmic sperm injection. Method of measurement: Electronic Microscope.;The evaluation of Gene expression of HAS-2, BAX, BCL-2, VCAN, ALCAM, R PTGS-2 in cumulus of oocyte. Timepoint: The day of pick up ovum. Method of measurement: Real time PCR.