The Role of Two- Dimensional Speckle Tracking Echocardiography in Prediction of Remodeling and Major Adverse Cardiovascular Events in ST Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention
试验速览
- 阶段
- 不适用
- 入组人数
- 204
- 主要终点
- The Incidence of major adverse cardiovascular events
研究概览
简要总结
ST-segment elevation myocardial infarction (STEMI) is a major cause of morbidity and mortality worldwide. In spite of decrease in acute and long-term mortality following STEMI in parallel with more use of reperfusion therapy, such as primary percutaneous coronary intervention (PPCI), modern antithrombotic therapy, and secondary prevention, mortality remains considerable. Reduced EF is a well-known predictor of increased short and long term major adverse cardiovascular events MACE :( heart failure, stroke and death)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ST elevation myocardial infarction patients after primary percutaneous coronary intervention
排除标准
- •Previous myocardial infarction.
- •Sever or haemodynamically significant (associated with chamber dilation) valvular heart diseases.
- •Previous heart failure.
- •Previous cerebrovascular strokes.
- •Atrial fibrillation.
- •Severe comorbidities as severe renal impairment, hepatic or respiratory failure.
- •Bad equality views which affects accurate speckle tracking imaging.
结局指标
主要结局
The Incidence of major adverse cardiovascular events
时间窗: 1 year
the rate of Acute coronary syndrome, Heart failure, Stroke and all-cause mortality
次要结局
未报告次要终点
研究者
Waleed Rafat Rasmy
Principal investigator
Assiut University
