跳至主要内容
临床试验/NCT04228510
NCT04228510Unknown不适用

The Role of Two- Dimensional Speckle Tracking Echocardiography in Prediction of Remodeling and Major Adverse Cardiovascular Events in ST Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention

Assiut University0 个研究点目标入组 204 人开始时间: 2020年3月最近更新:
适应症

试验速览

阶段
不适用
入组人数
204
主要终点
The Incidence of major adverse cardiovascular events

研究概览

简要总结

ST-segment elevation myocardial infarction (STEMI) is a major cause of morbidity and mortality worldwide. In spite of decrease in acute and long-term mortality following STEMI in parallel with more use of reperfusion therapy, such as primary percutaneous coronary intervention (PPCI), modern antithrombotic therapy, and secondary prevention, mortality remains considerable. Reduced EF is a well-known predictor of increased short and long term major adverse cardiovascular events MACE :( heart failure, stroke and death)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ST elevation myocardial infarction patients after primary percutaneous coronary intervention

排除标准

  • Previous myocardial infarction.
  • Sever or haemodynamically significant (associated with chamber dilation) valvular heart diseases.
  • Previous heart failure.
  • Previous cerebrovascular strokes.
  • Atrial fibrillation.
  • Severe comorbidities as severe renal impairment, hepatic or respiratory failure.
  • Bad equality views which affects accurate speckle tracking imaging.

结局指标

主要结局

The Incidence of major adverse cardiovascular events

时间窗: 1 year

the rate of Acute coronary syndrome, Heart failure, Stroke and all-cause mortality

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Waleed Rafat Rasmy

Principal investigator

Assiut University

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