Carotid Plaque Length to Predict Cardiovascular Events

Active, not recruiting

• Conditions: Coronary Artery Disease

• Registration Number: NCT05409209
• Lead Sponsor: Changhai Hospital

Brief Summary

This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No. 904 Hospital of the PLA Joint Logistics Support Force Wuxi). The study enrolled 5000 patients for suspected CAD who referred to coronary angiography from January 2017 through December 2018.

Detailed Description

Patients with coronary artery disease who were confirmed by coronary angiography were eligible for the study. Carotid ultrasonography was performed before coronary angiography, and carotid intima-media thickness (IMT), maximum thickness and length of all plaques were measured.

Study Timeline

• Study Start: 2017-01-01
• Primary Completion: 2021-12-31
• Status Verified: 2022-06
• Study First Submitted: 2022-06-03
• Study First Submitted QC: 2022-06-03
• Last Update Submitted: 2022-06-03
• Study First Posted: 2022-06-08
• Last Update Posted: 2022-06-08
• Study Completion: 2030-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

• Patients≥18 years old, those who underwent carotid ultrasonography and first coronary angiography simultaneously.

Exclusion Criteria

• Patients with known coronary artery disease, previous coronary or carotid revascularization, missing carotid ultrasound or coronary angiography results.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
major cardiovascular event	3 years	A composite of cardiovascular death, myocardial infarction, and ischemic stroke

Secondary Outcome Measures

Name	Time	Method
myocardial infarction	3 years
major vascular event	3 years	A composite of cardiovascular death, myocardial infarction, ischemic stroke, and coronary artery revascularization
cardiovascular death	3 years
ischemic stroke	3 years
coronary artery revascularization	3 years	coronary artery bypass grafting or percutaneous coronary intervention
all-cause death	3 years

Trial Locations

Locations (5)

No. 904 Hospital of the PLA Joint Logistics Support Force; 🇨🇳 Wuxi, Jiangsu, China

Changhai Hospital; 🇨🇳 Shanghai, Shanghai, China

Putuo Hospital; 🇨🇳 Shanghai, Shanghai, China

Gongli Hospital; 🇨🇳 Shanghai, Shanghai, China

Yueyang Hospital; 🇨🇳 Shanghai, Shanghai, China