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Cognitive Behavioral Therapy for COPD

Not Applicable
Completed
Conditions
COPD
Depression
Interventions
Behavioral: CLIMB (COPD Lifestyle, Mood, and Behavior)
Registration Number
NCT01694628
Lead Sponsor
University of Washington
Brief Summary

The purpose of this study in patients with advanced COPD and depression is twofold:

1. Determine the feasibility and acceptability of a 6-session e-counseling intervention

2. Determine the efficacy of the e-counseling intervention on depressive symptoms

We hypothesize that patients who participate in e-counseling will have improved depressive symptoms compared to patients receiving usual care at 8 weeks.

Detailed Description

Chronic obstructive pulmonary disease (COPD) is the third leading cause of the death in the US. Although COPD is mostly preventable, there is no cure. Thus, care of patients with COPD is primarily focused on symptom palliation with the goal of improving quality of life for both patients and their families. These goals are highly consistent with core principles of palliative care. Dyspnea is the most distressing symptom for patients. Even optimal disease-directed treatment provides only partial relief from dyspnea. Depression is consistently associated with worse dyspnea, but the mechanisms underlying this relationship are poorly understood. Since existing treatment for dyspnea has only limited success and there is evidence that treating depression alleviates pain, we propose that by improving mood, we may be more successful in alleviating dyspnea. Psychosocial-behavioral therapy (PBT) which is focused on increasing pleasant events and improving problem solving skills has been shown to have immediate and sustained effects on depressive symptoms in patients with dementia and post-stroke holds tremendous promise for efficacy in advanced COPD. Testing the use of novel technologies to provide efficacious interventions such as PBT to patients with advanced disease is critical for translational palliative care research

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
18
Inclusion Criteria
  • COPD (FEV1/FVC < 70% & FEV1 <80%; current or past smoking >10pack-years)
  • Depressed (PHQ-9 >=10)
  • Ability to speak, read and write English
  • Willingness to use computer or study-issued tablet device
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Exclusion Criteria
  • Current non-nicotine substance abuse or dependence
  • Psychotic disorder
  • Active suicide ideation with intent and plan
  • Alzheimer's/dementia
  • Currently receiving any psychotherapy
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
CLIMB (COPD Lifestyle, Mood, and Behavior)CLIMB (COPD Lifestyle, Mood, and Behavior)Counseling sessions for COPD and depression
Primary Outcome Measures
NameTimeMethod
Depressive Symptoms8 weeks

Personal Health Questionnaire-9

Secondary Outcome Measures
NameTimeMethod
Fatigue8 weeks

Chronic Respiratory Questionnaire

Quality of Life8 weeks

Chronic Respiratory Questionnaire and Medical Outcomes Short Form-36

Anxiety8 weeks

Hospital Anxiety and Depression Scale

Physical Activity8 weeks

Accelerometry (Stepwatch)

Dyspnea Intensity and Distress8 weeks

Chronic Respiratory Questionnaire, Shortness of Breath Questionnaire, Dyspnea Management Questionnaire

Trial Locations

Locations (1)

University of Washington

🇺🇸

Seattle, Washington, United States

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