Cognitive Behavioral Therapy for COPD
- Conditions
- COPDDepression
- Interventions
- Behavioral: CLIMB (COPD Lifestyle, Mood, and Behavior)
- Registration Number
- NCT01694628
- Lead Sponsor
- University of Washington
- Brief Summary
The purpose of this study in patients with advanced COPD and depression is twofold:
1. Determine the feasibility and acceptability of a 6-session e-counseling intervention
2. Determine the efficacy of the e-counseling intervention on depressive symptoms
We hypothesize that patients who participate in e-counseling will have improved depressive symptoms compared to patients receiving usual care at 8 weeks.
- Detailed Description
Chronic obstructive pulmonary disease (COPD) is the third leading cause of the death in the US. Although COPD is mostly preventable, there is no cure. Thus, care of patients with COPD is primarily focused on symptom palliation with the goal of improving quality of life for both patients and their families. These goals are highly consistent with core principles of palliative care. Dyspnea is the most distressing symptom for patients. Even optimal disease-directed treatment provides only partial relief from dyspnea. Depression is consistently associated with worse dyspnea, but the mechanisms underlying this relationship are poorly understood. Since existing treatment for dyspnea has only limited success and there is evidence that treating depression alleviates pain, we propose that by improving mood, we may be more successful in alleviating dyspnea. Psychosocial-behavioral therapy (PBT) which is focused on increasing pleasant events and improving problem solving skills has been shown to have immediate and sustained effects on depressive symptoms in patients with dementia and post-stroke holds tremendous promise for efficacy in advanced COPD. Testing the use of novel technologies to provide efficacious interventions such as PBT to patients with advanced disease is critical for translational palliative care research
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
- COPD (FEV1/FVC < 70% & FEV1 <80%; current or past smoking >10pack-years)
- Depressed (PHQ-9 >=10)
- Ability to speak, read and write English
- Willingness to use computer or study-issued tablet device
- Current non-nicotine substance abuse or dependence
- Psychotic disorder
- Active suicide ideation with intent and plan
- Alzheimer's/dementia
- Currently receiving any psychotherapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description CLIMB (COPD Lifestyle, Mood, and Behavior) CLIMB (COPD Lifestyle, Mood, and Behavior) Counseling sessions for COPD and depression
- Primary Outcome Measures
Name Time Method Depressive Symptoms 8 weeks Personal Health Questionnaire-9
- Secondary Outcome Measures
Name Time Method Fatigue 8 weeks Chronic Respiratory Questionnaire
Quality of Life 8 weeks Chronic Respiratory Questionnaire and Medical Outcomes Short Form-36
Anxiety 8 weeks Hospital Anxiety and Depression Scale
Physical Activity 8 weeks Accelerometry (Stepwatch)
Dyspnea Intensity and Distress 8 weeks Chronic Respiratory Questionnaire, Shortness of Breath Questionnaire, Dyspnea Management Questionnaire
Trial Locations
- Locations (1)
University of Washington
🇺🇸Seattle, Washington, United States