MedPath

Alpha-1 Foundation Research Registry

Completed
Conditions
Alpha 1-Antitrypsin Deficiency
Registration Number
NCT00499941
Lead Sponsor
Medical University of South Carolina
Brief Summary

The Alpha-1 Foundation Research Registry is a confidential database made up of individuals diagnosed with severe alpha-1 antitrypsin deficiency (Alpha-1) or the carrier state.

Detailed Description

The Registry was established in 1997 by the Alpha-1 Foundation to facilitate research initiatives and promote the development of improved treatments and a cure for Alpha-1. Located at the Medical University of South Carolina (MUSC) in Charleston, the Registry employs procedures that ensure the most stringent confidentiality of participants. The Registry operates under the direction of the Alpha-1 Foundation Board of Directors and is guided by an Advisory Committee comprised of leaders in the medical, ethical, scientific and Alpha communities. Individuals enrolled in the Registry have the ongoing opportunity to participate directly in clinical trials of new therapeutic approaches in addition to other research opportunities.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
6655
Inclusion Criteria
  • Individuals of all ages who are diagnosed with severe alpha-1 antitrypsin deficiency or the carrier state
Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To study the natural history of PiZZ, PiSZ, and PiMZ alpha-1 antitrypsin deficiencyNot limited
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Medical University of South Carolina. Division of Pulmonary and Critical Care Medicine

🇺🇸

Charleston, South Carolina, United States

© Copyright 2025. All Rights Reserved by MedPath