Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

• Conditions: Meniscus Injury
• Interventions: Procedure: Complete meniscectomy; Procedure: Subtotal meniscus resection; Procedure: Meniscus Suture; Procedure: Partial meniscus resection

• Registration Number: NCT04962555
• Lead Sponsor: Peking University Third Hospital

Brief Summary

Through the analysis of the data of 8094 patients with knee meniscus injury before December 31, 2008 and more patients with partial meniscus resection, subtotal resection and total resection, we can understand the gender difference and ratio of medial and lateral meniscus injuries. Differences, differences in locations, differences in tearing methods, differences in surgical methods, and the course of the disease affect the meniscus injury and surgical methods, and further affect the patient's knee degeneration imaging, accompanying cartilage injury, knee osteoarthritis, Partial resection, subtotal resection and meniscus regeneration after total resection, imaging and secondary arthroscopic exploration (Second-Look) were studied.

Detailed Description

Through the data of 8094 patients with knee meniscus injury who underwent surgery at the Institute of Sports Medicine of the Third Hospital of Beijing Medical University before December 31, 2008, and the patients who underwent meniscus suture, partial resection, subtotal resection, and total resection. Analyze and understand the influence of gender difference, ratio difference, position difference, tearing method difference, surgical method difference and disease course on the meniscus injury situation and operation method of the internal and lateral meniscus injury. Observation and research will also be conducted on reports of knee cartilage injury, knee osteoarthritis, and meniscus regeneration after partial meniscus resection, subtotal resection and total resection.

Study Timeline

• Study Start: 2016-08-01
• Status Verified: 2021-06
• Study First Submitted: 2021-06-27
• Study First Submitted QC: 2021-07-04
• Last Update Submitted: 2021-07-04
• Study First Posted: 2021-07-15
• Last Update Posted: 2021-07-15
• Primary Completion: 2022-10-01
• Study Completion: 2022-12-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 8778

Inclusion Criteria

Before December 31, 2008, patients who underwent surgery for meniscus injury in this institute and patients who underwent meniscus suture, partial resection, subtotal resection, and total resection.

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Exclusion Criteria

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Complete meniscectomy	Complete meniscectomy	The patient underwent complete meniscectomy
Subtotal meniscus resection	Subtotal meniscus resection	The patient underwent Subtotal meniscus resection
Meniscus Suture	Meniscus Suture	The patient underwent meniscus suture surgery
Partial meniscus resection	Partial meniscus resection	The patient underwent partial meniscus resection

Primary Outcome Measures

Name	Time	Method
Meniscus surgery method	During operation	Meniscus surgery methods include: partial resection, subtotal resection, total resection, and suture.
Cartilage damage	7 years after surgery	Second-look after operation to observe whether the cartilage is damaged. The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.
Meniscus regeneration	7 years after surgery	Second-look after operation to observe whether the meniscus is regenerating. The Meniscus regeneration is evaluated as yes or no, in which the meniscus shape is complete and no tear is defined as yes, and other conditions are defined as no.
Meniscus injury site	During operation	Observe the meniscus injury site during the operation, which is divided into: medial and lateral anterior horn, medial and lateral body, medial and lateral posterior horn, medial and lateral disc.
Types of Meniscus Injury	During operation	The types of meniscus injuries were observed during the operation, which were divided into longitudinal fissure, oblique fissure, spallation, radial fissure, and barrel shank tear.

Trial Locations

Locations (1)

Institute of Sports Medicine, Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China