Efficacy of Dexmedetomidine-Propofol Versus Ketamine-Propofol for Sedation During Gastrointestinal Endoscopy

Sohag University1 site in 1 country100 target enrollmentNovember 12, 2024

ConditionsPropofol

InterventionsDexmedetomidine-Propofol Ketamine-Propofol

DrugsDexmedetomidine-Propofol Ketamine-Propofol

Overview

Phase: Not Applicable
Intervention: Dexmedetomidine-Propofol
Conditions: Propofol
Sponsor: Sohag University
Enrollment: 100
Locations: 1
Primary Endpoint: intraoperative and postoperative monitoring of sedation during upper or lower gastrointestinal system endoscopy.
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

This study aims to compare efficacy of sedation between Dexmedetomidine-Propofol and Ketamine-Propofol combinations in the upper or lower gastrointestinal system endoscopy. We compare between 2 combinations as regard hemodynamic stability, post operative side effects as occurrence of delirium, nausea, vomiting, headache, hallucination or agitation.

Registry

clinicaltrials.gov

Start Date

November 12, 2024

End Date

June 11, 2025

Last Updated

last year

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Sohag University

Responsible Party

Principal Investigator

Ahmed Hany Hamed

Resident, Department of Anesthesia, Intensive Care and Pain management, Faculty of Medicine, Sohag University

Sohag University

Eligibility Criteria

Inclusion Criteria

•American Society of Anesthesiologists physical status I to II.
•Age between 18 and 60 years.
•Both sexes.

Exclusion Criteria

•Having severe heart, lung, liver disease, kidney failure, or bleeding disorder.
•Patients having fever, hypothermia or infection, electrolyte disorders, such as hypokalemia and hypocalcaemia, acid-base disorder, allergy to drugs to be used.