An Eye Tracking Study of Affective Disorder Patients With Suicide Risk

• Conditions: Suicide; Major Depressive Disorder; Bipolar Disorder
• Interventions: Behavioral: eye-tracking

• Registration Number: NCT03711045
• Lead Sponsor: Central South University

Brief Summary

This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among affective disorder patients including bipolar and unipolar depression. All the participants including health control will be assessed by clinical interviewing, self-report assessment, cognitive evaluation and eye-tracking task.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-09-01
• Status Verified: 2018-10
• Study First Submitted: 2018-10-11
• Study First Submitted QC: 2018-10-17
• Last Update Submitted: 2018-10-17
• Study First Posted: 2018-10-18
• Last Update Posted: 2018-10-18
• Primary Completion: 2019-12-31
• Study Completion: 2019-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Diagnostic and Statistical Manual,DSM-IV diagnosis of depression or Bipolar disorder
• BDI-II>20(Suicide and disorder control group); BDI-II<13，no history of depression(Health control)
• Informed consent
• suicide attempt in the past 6 months(suicide risk group)

Exclusion Criteria

• Current or past substance abuse, psychotic disorder,obsessive compulsive disorder , Post-Traumatic Stress Disorder, in the past 6 months
• History of epilepsy or head trauma
• Eye disorders
• History of electroconvulsive therapy in the past 4 weeks.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Disorder Control Group	eye-tracking	patients with affective disorders(eg. bipolar disorder, major depression disorder) and without suicide ideation or behavior.
Suicide Risk Group	eye-tracking	patients with affective disorders(eg. bipolar disorder, major depression disorder) also have a history of suicide attempt in the past 6 months.
Healthy Control Group	eye-tracking	-

Primary Outcome Measures

Name	Time	Method
eye movement performance during free-view task	1 hour	The first fixated location and latency(msec)of eah trial, the total dwell time(msec) in each interest areas(IAs) during the whole trial to assess the attentional bias in the experiment.

Secondary Outcome Measures

Name	Time	Method
Scores in self-report assessment:Beck Anxiety Inventory	5 minutes	This scale is aimed to assess the clinical anxieous symptom in the recent 7 days
Scores in self-report assessment:Beck Depression Inventory	5 minutes	This scale is aimed to assess the clinical depressive symptom in the recent 7 days.
Scores in self-report assessment:Barratt Impulsiveness Scale	5 minutes	This scale is aimed to assess participant's impulsive trait.
Scores in self-report assessment:Ruminative Response Scale	5 minutes	This scale is aimed to assess participant's ruminative thinking process.

Trial Locations

Locations (1)

Mental Health Institute & Faculty of Psychiatry of The Second Xiangya Hospital, Central South University; 🇨🇳 Changsha, Hunan, China