Investigation of the influence of intraoperative mechanical ventilation on volatile organic compounds in the exhaled air
- Conditions
- Ventilator induced lung injury
- Registration Number
- DRKS00017508
- Lead Sponsor
- niverstitätsklinikum des Saarlandes, Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting stopped after recruiting started
- Sex
- All
- Target Recruitment
- 20
• Patients undergoing elective surgery
• Written consent of the patient
• Age = 18 years
• ASA I-III
• No participation in another study (up to 30 days before inclusion in the study)
• Total Intravenous Anesthesia (TIVA) with propofol and remifentanil
• BMI = 35kg / m²
• Inclusion criteria depending on the patient group:
o Planned operating time> 4 hours
o Planned surgery that requires one-lung ventilation
o Planned laparoscopic surgery
• rejection by the patient
• pre-existing conditions or patient circumstances that make a patient's examination impossible or meaningless (for example, dementia, psychiatric disorders, lack of speech or speaking skills)
• ASA> III
• drug abuse
• Positive HIV or hepatitis test
• Isolation of the patient
• pregnancy
• contraindications or known incompatibilities with intravenous narcotics used
• contraindications for total intravenous anesthesia
• Anesthesia guided by volatile anesthetics
• BMI> 35kg / m²
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Influence of mechanical ventilation on the exhaled pentanal concentration
- Secondary Outcome Measures
Name Time Method Changes in the exhaled volatile organic compounds by mechanical ventilation