To evaluate if Procalcitonin is a reliable marker to diagnose Sepsis Syndrome in oral and maxillofacial infections.
Phase 3
Completed
- Conditions
- Health Condition 1: A488- Other specified bacterial diseases
- Registration Number
- CTRI/2023/08/056876
- Lead Sponsor
- DrNupoor Sanjaykumar Meher
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
Patients with swelling of the face and/or neck that suggested an abscess or cellulitis complaining of one or more of the following symptoms: a compromised airway, restricted mouth opening, dysphagia, or body temperature greater than 38 °C will be admitted and will be included in the study.
Exclusion Criteria
Patient unwilling to be a part of the study. Patients with non-maxillofacial infection.
Known cases of neuroendocrine tumors, medullary thyroid cancer, small cell lung cancer, carcinoid syndrome, noninfectious systemic inflammation like inhalational injury, pulmonary aspiration, pancreatitis, heat stroke, mesenteric infarction, trauma, mechanical injury, burns, recent surgery.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Procalcitonin level can be increased at the time of admission due to presence of active infection <br/ ><br>The level can define the status of systemic spread of infection & aid to decide the antibiotic regimeTimepoint: PCT test will be done at the time of admission
- Secondary Outcome Measures
Name Time Method Procalcitonin level can be decreased at the time of discharge due drainage of pus & administration of antibiotics <br/ ><br>Antibiotics can be stopped after PCT level is decreased to avoid antibiotic resistance due to overdosageTimepoint: PCT test will be done at the time of discharge