Postprandial vascular inflammation after high-fat meal in healthy subjects
Not Applicable
- Conditions
- healthy adults
- Registration Number
- JPRN-UMIN000022103
- Lead Sponsor
- Tokyo Medical and Dental University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
- Smokers - Taking medications and supplements known to affect plasma lipids - No overnight-fasting - Food allergy for wheat, egg, peanuts, orange, walnuts, soy beans, apple, and peach
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method After an overnight fast, a fasting venous blood sample is drawn. 20 healthy adults intake the high-fat diet containing 28.5 g of fat. Blood samples are obtained at 1, 2, 4 h after fat intake. The vascular inflammatory parameters for plasma lipid, lipoprotein, apolipoprotein, C3, C5a, inflammatory markers, leukocyte numbers are measured in the fasting and the postprandial state.
- Secondary Outcome Measures
Name Time Method