Efficacy of different schemes of supplementation with micronutrient powder for the control of anemia and micronutrient deficiency in childre
- Conditions
- AnemiaNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN47136464
- Lead Sponsor
- Micronutrient Initiative (Canada)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 400
1. Children between 6 months and 11 months and 29 days old
2. Residents in the city of Cajamarca and communities near the Health Center Baños del Inca
3. Born at term
4. Birth weight = 2500 g
5. Healthy
6. Hemoglobin> 8 g/dL (corrected for altitude)
7. Weight / length> -2 SD
8. Parents agree and sign the informed consent form
1. Children younger than 6 months, or more than 12 months
2. Non-residents in Cajamarca (intervention site)
3. Children with initial hemoglobin below 8 g/dL (corrected for altitude) will be evaluated by the doctor to discard additional pathology and will be treated according to Ministry of Health standards
4. Weight/length below - 2 DE
5. Chronic, congenital or severe diseases
6. Parents do not sign the informed consent form
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Anemia prevalence. All children are followed for 12 months, at entry and every month children are examined by a pediatrician at the outpatient clinic, every 2 weeks a field worker visits the child´s home to record compliance and morbidity, at entry and at the end of supplementation a venous blood sample of 5 ml is taken to measure hemoglobin, and micronutrients. In 2 more times we will take a drop of blood from the finger to measure hemoglobin.
- Secondary Outcome Measures
Name Time Method 1. Growth (weight and length)<br>2. diarrhea prevalence<br>3. micronutrient status (ferritin, transferrin receptors)<br>4. vitamin A<br>5. vitamin B12<br>6. zinc and folate status<br>7. inflamatory markers (CRP, AGP)