Study for mechanism of electroacupuncture intervention based on PD-1 pathway for immune disorder of sepsis
Phase 1
Not yet recruiting
- Conditions
- Sepsis
- Registration Number
- ITMCTR1900002479
- Lead Sponsor
- The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Patients admitted to the intensive care unit (ICU) of The Second Affiliated Hospital of Guangzhou University of Chinese Medicine and diagnosed with sepsis;
2. Aged 18-85 years old;
3. Sign the informed consent.
Exclusion Criteria
1. Pregnancy or mentally illness;
2. Immunodeficiency patients; Using hormones or immunosuppressants;
3. HIV-ab positive;
4. Unwilling to participate in the trial or cooperate with treatment.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie electroacupuncture's effect on PD-1 pathway in sepsis immune dysfunction?
How does electroacupuncture compare to standard immunomodulatory therapies for sepsis-induced immune suppression?
Which biomarkers correlate with PD-1 pathway modulation during electroacupuncture treatment in septic patients?
What adverse events are associated with electroacupuncture targeting PD-1 in sepsis clinical trials?
Are there synergistic effects when combining electroacupuncture with PD-1 checkpoint inhibitors for sepsis management?