TCTR20230510003CompletedPhase 4
The effectiveness of intravenous dexamethasone prophylaxis before thyroidectomy in reducing postoperative pain, nausea and vomiting
Hua Hin Hospital0 sites100 target enrollmentStarted: May 10, 2023Last updated:
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 100
Study Overview
Brief Summary
In dexamethasone group, the mean pain score is significantly lower at recovery room admission and postoperative nausea and vomiting incidence is significantly lower at one hour after surgery compare to placebo group. No significantly differences in pain score and nausea and vomiting score at eight hours after surgery.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 Years to 65 Years (—)
- Sex
- All
Inclusion Criteria
- •1. Patients age 18-65 years who underwent thyroid surgery, 2. ASA class 1 or 2, 3. Ideal Body Weight 40-80 kilogram
Exclusion Criteria
- •1. Patients with previous thyroid or neck surgery, 2. antiemetic consumption within 48 hours before surgery, 3. history of chronic pain, 4. history of DM or preoperative blood glucose more than 126 mg/dL, 5. history of postoperative nausea and vomiting, 6. pregnancy or lactation, 7. history of allergic reaction to medication used in this research, 8. history of underlying diseases that may be worsen by dexamethasone administration i.e. gastric ulcer
Investigators
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