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Clinical Trials/TCTR20230510003
TCTR20230510003CompletedPhase 4

The effectiveness of intravenous dexamethasone prophylaxis before thyroidectomy in reducing postoperative pain, nausea and vomiting

Hua Hin Hospital0 sites100 target enrollmentStarted: May 10, 2023Last updated:
Conditions

Trial Snapshot

Phase
Phase 4
Status
Completed
Sponsor
Enrollment
100

Study Overview

Brief Summary

In dexamethasone group, the mean pain score is significantly lower at recovery room admission and postoperative nausea and vomiting incidence is significantly lower at one hour after surgery compare to placebo group. No significantly differences in pain score and nausea and vomiting score at eight hours after surgery.

Study Design

Study Type
Interventional

Eligibility Criteria

Ages
18 Years to 65 Years (—)
Sex
All

Inclusion Criteria

  • 1. Patients age 18-65 years who underwent thyroid surgery, 2. ASA class 1 or 2, 3. Ideal Body Weight 40-80 kilogram

Exclusion Criteria

  • 1. Patients with previous thyroid or neck surgery, 2. antiemetic consumption within 48 hours before surgery, 3. history of chronic pain, 4. history of DM or preoperative blood glucose more than 126 mg/dL, 5. history of postoperative nausea and vomiting, 6. pregnancy or lactation, 7. history of allergic reaction to medication used in this research, 8. history of underlying diseases that may be worsen by dexamethasone administration i.e. gastric ulcer

Investigators

Sponsor
Hua Hin Hospital

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