Pre-Operative Acetazolamide Administration for Post-Operative Abdominal Pain Releif
Phase 2
- Conditions
- cholecystitis.Cholecystitis
- Registration Number
- IRCT2017081935778N1
- Lead Sponsor
- Vice Chancellor for research of Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 111
Inclusion Criteria
Subjects must be candidates for laparoscopic cholecystectomy (ages 18 to 65)
Exclusion criteria:
Subject with a history of any hematologic disorders; chronic metabolic acidosis; chronic obstructive pulmonary disease; kidney transplantation; allergy to sufonamides; patients with present history of electrolyte disturbances; CNS dysfunction; renal failure or creatinine level higher than 2mg/dl; pregnancy; any liver diseases; or patients with ongoing diuretic treatment.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Abdominal Pain. Timepoint: first, second, and third 30 minutes within the operation, and first,second, and third 30 minutes within recovery, also at the time of discharge. Method of measurement: VAS questionnaire.;Modified Aldrete Score. Timepoint: first, second, and third 30 minutes within the operation, and first,second, and third 30 minutes within recovery, also at the time of discharge. Method of measurement: Physical examination for scoring; and pulse oxymetry.
- Secondary Outcome Measures
Name Time Method Time before requesting opioid. Timepoint: first, second, and third 30 minutes within the operation, and first,second, and third 30 minutes within recovery, also at the time of discharge. Method of measurement: Timer.;Amount of opioid used to deteriorate pain. Timepoint: first, second, and third 30 minutes within the operation, and first,second, and third 30 minutes within recovery, also at the time of discharge. Method of measurement: Report by resident.;Distribution of pain location. Timepoint: first, second, and third 30 minutes within the operation, and first,second, and third 30 minutes within recovery, also at the time of discharge. Method of measurement: Physical Examination.;Time before discharge from hospital. Timepoint: first, second, and third 30 minutes within the operation, and first,second, and third 30 minutes within recovery, also at the time of discharge. Method of measurement: Timer.