Peptidomics Profile Characterization and Diagnostic Model Construction of Heart Failure

Phase 1

• Conditions: Heart Failure

• Registration Number: ITMCTR2000003344
• Lead Sponsor: Hunan University of Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

1. Meet the criteria of heart failure diagnosis in 2018 China heart failure diagnosis and treatment guidelines.
2. The State Administration of traditional Chinese Medicine issued TCM clinical pathway and TCM diagnosis and treatment plan (2017 version) for the TCM diagnosis and treatment plan of heart failure to carry out TCM syndrome differentiation and type diagnosis.
3. Adopt the new classification and diagnosis standard of heart failure. According to the level of ejection fraction (EF), heart failure can be divided into heart failure with decreased ejection fraction (hfref, EF < 40%), heart failure with preserved ejection fraction (HFPEF, EF > 50%), and heart failure with ejection fraction in the critical range of 40% - 49% (hfmref).

Exclusion Criteria

1. The elderly over 90 years old;
2. Patients with renal insufficiency;
3. Patients with malignant tumors.

Study & Design

• Study Type: Diagnostic test
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proteomics of plasma and urine;SEN, SPE, ACC, AUC of ROC;