Effect of Nebulized Heparin in Patients with Pneumonia
Phase 2
Recruiting
- Conditions
- Pneumonia.Ventilator associated pneumoniaJ95.851
- Registration Number
- IRCT20200821048470N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Patients with pneumonia who have been intubated and admitted to the ICU.
All patients have an apache score less than 25.
Exclusion Criteria
Thrombocytopenia or a history of heparin-induced thrombocytopenia
Coagulation disorder with INR above 1.5
pregnant women
Any active bleeding and history of intracranial hemorrhage during the last 3 months
Patients receiving anticoagulants
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The degree of obstruction of the endotracheal tube by plug or bare mucus. Timepoint: On admission and daily. Method of measurement: Clinical Information Collection Form.;Hypoxia. Timepoint: On admission and daily. Method of measurement: Drop in arterial blood oxygen saturation to less than 90 or more than 4% of basal level after elimination of other common causes.;Infection. Timepoint: On admission and daily. Method of measurement: New VAP event based on different clinic or graph with primary lung infection.
- Secondary Outcome Measures
Name Time Method