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Effect of Nebulized Heparin in Patients with Pneumonia

Phase 2
Recruiting
Conditions
Pneumonia.
Ventilator associated pneumonia
J95.851
Registration Number
IRCT20200821048470N1
Lead Sponsor
Ahvaz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
40
Inclusion Criteria

Patients with pneumonia who have been intubated and admitted to the ICU.
All patients have an apache score less than 25.

Exclusion Criteria

Thrombocytopenia or a history of heparin-induced thrombocytopenia
Coagulation disorder with INR above 1.5
pregnant women
Any active bleeding and history of intracranial hemorrhage during the last 3 months
Patients receiving anticoagulants

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The degree of obstruction of the endotracheal tube by plug or bare mucus. Timepoint: On admission and daily. Method of measurement: Clinical Information Collection Form.;Hypoxia. Timepoint: On admission and daily. Method of measurement: Drop in arterial blood oxygen saturation to less than 90 or more than 4% of basal level after elimination of other common causes.;Infection. Timepoint: On admission and daily. Method of measurement: New VAP event based on different clinic or graph with primary lung infection.
Secondary Outcome Measures
NameTimeMethod
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