ISRCTN81931394
Completed
未知
An unblinded, two-arm randomised controlled trial to determine the effectiveness and cost-effectiveness of antimicrobial impregnated (with rifampicin and miconazole) long lines (termed peripherally inserted central venous catheters, or AM-PICC) compared with standard PICC (S-PICC) for reducing blood stream infection (BSI)
Great Ormond Street Hospital for Children NHS Foundation Trust (UK)0 sites861 target enrollmentNovember 21, 2014
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Infectious disease, preterm babies requiring a PICC
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust (UK)
- Enrollment
- 861
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/31040096 (added 02/05/2019)
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Babies who require a PICC (Premicath 1 Fr)
- •2\. Admitted to a NNU that is recruiting for this trial
- •3\. Parent/legal representative of the baby gives informed written consent for the trial
- •Note: Babies with the following can be included in the trial:
- •1\. Congenital malformations
- •2\. Gastrointestinal surgical conditions
- •3\. Previous PICC (non\-trial PICC)
- •4\. Previously treated BSI which has resolved in the opinion of the Investigator
Exclusion Criteria
- •1\. Baby has been previously entered into this trial
- •2\. Baby has a known allergy or hypersensitivity to rifampicin or miconazole
Outcomes
Primary Outcomes
Not specified
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