PREVAIL study - PREVenting infection using Antimicrobial Impregnated Long lines

Not Applicable

Completed

• Conditions: Infectious disease, preterm babies requiring a PICC; Neonatal Diseases

• Registration Number: ISRCTN81931394
• Lead Sponsor: Great Ormond Street Hospital for Children NHS Foundation Trust (UK)

Brief Summary

2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/31040096 (added 02/05/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-11-21
• Study Completion: 2017-08-31
• Last Update Posted: 27 May 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 861

Inclusion Criteria

1. Babies who require a PICC (Premicath 1 Fr)
2. Admitted to a NNU that is recruiting for this trial
3. Parent/legal representative of the baby gives informed written consent for the trial

Note: Babies with the following can be included in the trial:
1. Congenital malformations
2. Gastrointestinal surgical conditions
3. Previous PICC (non-trial PICC)
4. Previously treated BSI which has resolved in the opinion of the Investigator

Exclusion Criteria

1. Baby has been previously entered into this trial
2. Baby has a known allergy or hypersensitivity to rifampicin or miconazole

Study & Design

• Study Type: Interventional
• Study Design: Not specified