Change of oral environment according to antibacterial effect of Lespedeza cuneata extract
- Conditions
- Not Applicable
- Registration Number
- KCT0007379
- Lead Sponsor
- Kangwon National University
- Brief Summary
Application of mouthwash containing Lespedeza cuneata extract significantly decreased clinical values in all indicators of oral microbes, O’Leary index, PI, and GI (p<0.05). In addition, after gargling with a mouthwash containing Lespedeza cuneata extract, the antibacterial action on Gram-negative and Gram-positive bacteria that cause oral disease showed an excellent clinical effect in inhibiting, preventing, and treating oral diseases. The use of the mouthwash containing Lespedeza cuneata extract was found to be effective for oral desease related indicators and bacteria causing oral disease. Therefore, using a mouthwash containing Lespedeza cuneata extract, a natural drug, will possibly maintain healthy oral health by inhibiting and preventing the progression of oral disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 63
Participants in this study were healthy individuals without systemic disease among patients who agreed to fill out the questionnaire.
Among the study participants, those with severe dental diseases (such as periodontitis, dental caries, dry mouth, etc.) (except for one or more dental caries), those who are currently treated for liver disease, kidney disease, Schogren's syndrome, and antibiotics within 2 months) were excluded.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mmicrobiological analysis
- Secondary Outcome Measures
Name Time Method O’Leary index ;Plaque index (PI) ;Evaluation of improvement by test subjects themselves;Gingival index (GI) ;Cariview